Overview

Anticoagulation therapy is essential for the prevention of fatal blood clots, especially following a heart attack, stroke, or pulmonary embolism. Patients taking anticoagulation drugs require regular clinical monitoring of their blood coagulation status to inform proper drug dosing and maintain a safe homeostasis of coagulation and bleeding. Anticoagulation monitoring is not well suited for low-resource settings because patients are required to regularly commute to community hospitals at least three times per week to get their blood tested. In rural Kenya, for example, patients live on average two hours from a community hospital, which confers a time and transportation cost burden to the patient and their family. We are engineering anticoagulation monitoring technologies that enable the affordable, portable assessment of a patient’s coagulation status rapidly and easily within low-resource settings. Our device uses optical techniques and integrates with standard cellphone cameras to measure blood clotting time from only microliters of capillary blood. The team comprises of HST graduate students Mohamad Najia and Shriya Srinivasan. We are collaborating with Dr. Rachel Rosovsky, an expert hematologist at MGH and Dr. Aparna Ramanathan, an MGH Global Health Fellow who practices half the year at Sagam Community Hospital in Kenya. Learn more at sanviato.com